Salary: 20-30k
Experience requirements:5-10 years
Educational requirements:PhD
Job Description:
1. Job Responsibilities
1) Responsible for the structural design, process development, material synthesis, and production of ADC product Linker Payload, non natural amino acid platform, and long-acting side chains
2) Responsible for the structural design, process development, material synthesis, and production of non natural amino acids
3) Responsible for the development, optimization, and pilot production of coupling processes for ADC products and non natural amino acid platform projects
4) Responsible for communication and progress control of chemical synthesis and coupling outsourcing projects
5) Participate in the construction of commercial production lines, coupling and chemical related content, including communication with design companies, equipment suppliers, equipment URS writing, equipment bidding and tendering, etc
6) Responsible for the registration and application work related to chemistry and coupling in the application materials
7) Guide and review project design proposals, as well as stage summaries and plans, to grasp overall progress and direction
8) Guide and review the selection and procurement of laboratory equipment, as well as the procurement of consumables and reagents
2. Job Qualifications
1) Major in pharmaceutical chemistry, organic chemistry synthesis, fine chemistry applied chemistry, etc., with a master's degree or above, more than 8 years of experience in chemical research and development, rich experience in coupling toxins and antibodies in ADC, and more than 3 years of management experience
2) Master knowledge in drug synthesis analysis, instrument use and maintenance, biochemical reagent use, laboratory safety, and other aspects
3) Familiar with organic synthesis unit operations, strong analytical and problem-solving skills, and understanding of laboratory operating procedures; Proficient in writing experimental reports and official documents, as well as literature search and analysis skills
4) Master experimental design and analysis skills; Proficient in using English for listening, speaking, reading, and writing. Has good communication, coordination, and execution skills
5) Strong planning, organizational and coordination skills, communication skills, execution skills, and interpersonal communication abilities
6) Serious and responsible, fair and objective, rigorous and steady, with a strong sense of confidentiality, able to withstand significant work pressure