Salary: strong>0-0K
Experience requirements: Strong>3-5 years
Educational requirements: PhD or above
Job Description: strong>
Job Responsibilities:
1. Responsible for the construction and daily operation of CADD/AIDD R&D platform, expanding its application scenarios in the company's new drug research and development
2. Independently complete tasks such as protein small molecule interaction analysis, protein conformational change analysis, molecular docking, protein dynamics simulation, virtual screening, and molecular structure design
3. Design and conduct computer simulation experiments to evaluate the ADMET properties of drugs
4. Work closely with the pharmaceutical research and development team to provide ideas for new drug development projects, especially for the discovery of promising compounds
5. Work closely with the biological research and development team to assist in project research targeting new targets and mechanisms of action
6. Collect and organize relevant data on internal and external drug development, and conduct data mining and analysis to provide support for drug development decisions
7. Track the development trends of CADD/AIDD research and development at home and abroad, develop and introduce new technologies and methods, continuously improve and update workflow and tools
8. Assist in developing research plans, analyzing experimental results, and writing research reports
9. Participate in the construction and maintenance of the company's compound information system
Job requirements:
1. Hold a doctoral degree in computational chemistry, computational biology, computer-aided drug design, AI drug design, medicinal chemistry, or organic chemistry
2. Three years or more of CADD/AIDD experience in the field of new drug development, with team management experience preferred
3. Familiar with the new drug development process and have a deep understanding of the various application scenarios of CADD/AIDD in the field of new drug development
4. Proficient in computer-aided drug development tools and software, including but not limited to molecular docking programs such as AutoDock, molecular dynamics simulation software such as AMBER, and quantum chemistry calculation software such as Gaussian Schr? Drug design related software such as Dinger
5. Experience in developing computational methods for biological systems is preferred, which means in-depth research or improvement of computational programs, including but not limited to molecular simulations, free energy calculations, protein docking, structural prediction, and other programs
6. Skilled in learning new knowledge, tracking the latest developments in drug research and breakthrough technologies both domestically and internationally, and applying open-source data and methods to practical work
7. Strong written and oral communication skills in both Chinese and English
8. Results oriented, with strong communication skills and teamwork spirit
Please send your CV or resume as an attachment to the following email address:
mailto: rbhr@hrcenter.co.uk
With the subject line formatted as: 'Name + Position + Company Name + Location'.